Automated lamina cribrosa microstructural segmentation in optical coherence tomography scans of healthy and glaucomatous eyes.

نویسندگان

  • Zach Nadler
  • Bo Wang
  • Gadi Wollstein
  • Jessica E Nevins
  • Hiroshi Ishikawa
  • Larry Kagemann
  • Ian A Sigal
  • R Daniel Ferguson
  • Daniel X Hammer
  • Ireneusz Grulkowski
  • Jonathan J Liu
  • Martin F Kraus
  • Chen D Lu
  • Joachim Hornegger
  • James G Fujimoto
  • Joel S Schuman
چکیده

We demonstrate an automated segmentation method for in-vivo 3D optical coherence tomography (OCT) imaging of the lamina cribrosa (LC). Manual segmentations of coronal slices of the LC were used as a gold standard in parameter selection and evaluation of the automated technique. The method was validated using two prototype OCT devices; each had a subject cohort including both healthy and glaucomatous eyes. Automated segmentation of in-vivo 3D LC OCT microstructure performed comparably to manual segmentation and is useful for investigative research and in clinical quantification of the LC.

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In vivo lamina cribrosa micro-architecture in healthy and glaucomatous eyes as assessed by optical coherence tomography.

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عنوان ژورنال:
  • Biomedical optics express

دوره 4 11  شماره 

صفحات  -

تاریخ انتشار 2013